Pregnant women in their first and early second trimesters may experience nausea
and vomiting, commonly referred to as "morning sickness." It is estimated that
nausea affects between 70 and 85% of pregnant women and vomiting approximately
50%.
Key messages
􀃎 The evidence suggests that anti-emetic medication (particularly antihistamines
and vitamin B6) reduce the frequency of nausea in early pregnancy by
84%.
􀃎 There have been relatively few studies reporting on side effects of antiemetics
and foetal outcomes such as growth and congenital malformations.