Preeclampsia is defined as hypertension associated with proteinuria during de
second half of pregnancy. It occurs in 2 - 8% of cases and could affect kidneys and
other maternal organs such as liver, brain and placenta.
Preeclampsia is associated with a significant increase in morbidity and
mortality of mothers and newborns.
There is insufficient evidence for reliable conclusions about the use of a
donor or precursor of nitric oxide to prevent preeclampsia and its
The use of nitric oxide produces important side effects (headache)
More studies including greater numbers of women and conducted in
different settings are needed to assess whether nitric oxide reduces the risk
of preeclampsia and its complications.