Intra-amniotic infection (IAI) (or chorioamnionitis) complicates up to 10% of all
pregnancies and up to 2% of labors at term. There is a significant risk of complications
for the mother and the neonate following IAI, including sepsis and pneumonia.
Intraamniotic infection (IAI) is associated with significant risk of both maternal
and perinatal morbidity and mortality.
There is insufficient evidence from trials to indicate which antibiotic is best
and whether or not it should be given intrapartum or postpartum.
While this review was not conclusive it seems appropriate to start antibiotics
to women with clinical IAI because the consequences of not doing so are potentially
There is a need for more studies in low-income countries to evaluate optimal