Rates of preterm birth range between 6% and 12% in developed countries,
and can be generally higher in developing countries. Bacterial vaginosis
during pregnancy has been implicated as one of the underlying factors
associated with preterm delivery.
Key messages
Bacterial vaginosis during pregnancy is implicated in preterm birth, the leading
cause of neonatal mortality in both developed and developing countries.
There are evidence that antibiotic treatment of bacterial vaginosis reduce the
incidence of prelabour rupture of membranes, low birth weight and preterm
birth.
Further research is needed to clarify whether screening and treatment of bacterial
vaginosis before 20 weeks’ gestation improves maternal and neonatal
outcomes, especially in under-resourced settings.