Development of a Molecular Diagnostic Method of Trypanosomacruzi Infection for neonatal detection of congenital Chagas
2015 - 2017
Period: 2015 – 2017
Researchers
Maria Luisa Cafferata
Goal
Develop and validate a molecular diagnostic method for infection by Trypanosomacruzi with application to congenital Chagas
Methodology
It is proposed to conduct a prospective study in 4-6 public hospitals in the Argentine Republic. At the time of delivery, we will recruit women who are seropositive for HIV infection. T. cruzidetected during pregnancy or at the time of delivery by routine serological screening systems in the hospitals called for this phase of the study (two serological techniques). We will collect umbilical cord blood to measure antibodies of maternal origin, examine and follow the children until they are 10 months old.
Study sites:
Our Lady of Mercedes Maternity Institute, San Miguel de Tucumán
La Banda Maternity Hospital, Santiago del Estero
Regional Maternity, Santiago del Estero
JR Vidal Hospital, Corrientes
Perrando Hospital, Chaco